Semaglutide
Long-acting GLP-1 receptor agonist — incretin metabolic research
How researchers describe Semaglutide
Acts at the GLP-1 receptor (class-B GPCR). Albumin-binding C18 diacid side chain extends circulating half-life vs native GLP-1 in published rodent and primate work. Engages cAMP/PKA and PI3K/Akt downstream of GLP-1R in pancreatic β-cell and hypothalamic models.
- GLP-1 receptor (class-B GPCR) → cAMP / PKA
- Albumin-binding C18 diacid extended half-life
- β-cell insulinotropic + central satiety signaling
Lyophilized: −20°C, light-protected. Reconstitution and stability are set by the end researcher; no use-window or dosing guidance is provided.
Per-lot HPLC + LC-MS tested
- HPLC + LC-MS laboratory analysis on every lot
- Reported purity ≥99.0%
- Lot-traceable COA available on request
- Sealed glass vial, butyl stopper, crimp cap
- Marso et al., 2016 — Semaglutide and cardiovascular outcomes in type 2 diabetes (SUSTAIN-6), N Engl J Med
- Knudsen & Lau, 2019 — The discovery and development of liraglutide and semaglutide, Front Endocrinol
Common researcher questions
Is this for human use?+
No. All X Factor research peptides are RUO — sold solely for in-vitro and non-clinical preclinical research. Not for human or veterinary use, food, supplement, cosmetic, or therapeutic application.
How is purity verified?+
Every lot is analyzed per lot by HPLC (and MS where applicable). COA available per lot — request via contact form.
How is it shipped?+
Lyophilized peptide in a sealed glass vial, packed in discreet outer packaging, shipped from our US fulfillment partner. Blends ship with cold-pack on request.
Can I get a COA before ordering?+
Yes — contact us with the SKU and we will email the most recent lot COA. We also publish the COA vault to verified researchers post-purchase.
Restock for OOS items?+
Use the Notify-Me form on the catalog page. We email when the lot is QC-passed and live. No spam, single-use.