MOTS-c
16-amino-acid mitochondrial-derived peptide — AMPK metabolic signaling
How researchers describe MOTS-c
Reported in preclinical literature to translocate to the nucleus under metabolic stress and modulate AMPK / folate-methionine cycle activity. Activates AMPK in skeletal muscle in rodent models and improves glucose-handling endpoints in published in-vitro and in-vivo work.
- AMPK energy-sensing activation
- Folate–methionine one-carbon cycle modulation
- Nuclear translocation under metabolic stress
Lyophilized: −20°C, light-protected. Reconstituted: refrigerated, used within 30 days per typical protocol literature.
Independent US lab tested
- ✓ Independent US laboratory analysis (HPLC, MS) per lot
- ✓ Reported purity ≥99.4%
- ✓ Lot-traceable COA available on request
- ✓ Sealed glass vial, butyl stopper, crimp cap
- Lee et al., 2015 — MOTS-c promotes metabolic homeostasis and reduces insulin resistance, Cell Metab
- Reynolds et al., 2021 — MOTS-c, an exercise-induced regulator of age-dependent physical decline and muscle homeostasis, Nat Commun
What labs are saying
Common researcher questions
Is this for human use?+
No. All X Factor research peptides are RUO — sold solely for in-vitro and non-clinical preclinical research. Not for human or veterinary use, food, supplement, cosmetic, or therapeutic application.
How is purity verified?+
Every lot is analyzed by an independent US laboratory using HPLC (and MS where applicable). COA available per lot — request via contact form.
How is it shipped?+
Lyophilized peptide in a sealed glass vial, packed in discreet outer packaging, shipped from our US fulfillment partner. Blends ship with cold-pack on request.
Can I get a COA before ordering?+
Yes — contact us with the SKU and we will email the most recent lot COA. We also publish the COA vault to verified researchers post-purchase.
Restock for OOS items?+
Use the Notify-Me form on the catalog page. We email when the lot is QC-passed and live. No spam, single-use.